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小豆It is an ancient cultivated crop originated in my country，Plays an important role in my country’s grain production and food processing industry。Professor Wan Ping of our school led his team to carry out adzuki bean genetic breeding work for many years，Joint Institute of Genetics and Developmental Biology, Chinese Academy of Sciences、BGI and International Semi-Arid Crops Research Institute，After more than two years of research，Be the first to complete the whole genome sequencing of adzuki bean，Drawing a high-quality draft of the adzuki bean genome，Analysis of the molecular mechanism of starch and fat accumulation in adzuki bean grains，This research result has been published10month12In Proceedings of the National Academy of Sciences (Proceedings of the National Academy of Sciences of the United States of America) magazine published online.

Adzuki beans are different from other leguminous crops such as soybeans,Very low fat content, average only0.59%, while the total starch content is higher, average57.06%%. also,小豆Protein content16.9～28.6%, dietary fiber content4.8～7.7%, essential protein for human body8Amino acid content is the highest among cereal crops2～3times, richerBVitamins,Iron、Calcium and other minerals and terpenes、Isoflavones、Saponins and other biologically active substances，Is ideal high protein, low fat, multi-nutrient,Replenish blood,Multi-functional food.Li Shizhen's "Compendium of Materia Medica" and "Chinese Pharmacopoeia" record that adzuki beans have the ability to remove dampness、Detoxification、Medicinal effects such as reducing swelling，Modern medical research shows that adzuki beans can lower blood sugar、Lower blood lipids、Weight loss and anti-tumor effects。Currently,Adzuki beans are grown in more than 30 countries around the world，Its reproductive period is short，Wide adaptability，resistant to barrenness，Improving dietary structure、Adjust the planting structure and farming system、Resource-saving agriculture、Nitrogen fixation and environmental protection、It plays an important role in developing agriculture for export and earning foreign exchange。China is the world’s largest producer and exporter of adzuki beans，Export volume accounts for about 80% of the world's total，Products are sold to more than 30 countries and regions around the world。

Beinong Adzuki Bean scientific research team started from Professor Jin Wenlin in the 1980s，Have been engaged in adzuki bean research for more than 30 years，In the National Natural Science Foundation of China、Ministry of Agriculture、Beijing Science and Technology Commission、Agricultural Committee、With the strong support of the Education Committee，Cultivation of Jingnong No. 2、Jingnong No. 5、Jingnong No. 6、Jingnong No. 7 and Jingnong No. 8 adzuki bean varieties，Collected more than 1,000 Chinese and foreign adzuki bean resources，Evaluation of adzuki bean germplasm、Leading the field in innovation and mining utilization research。In the past two years，The teamShotgun sequencing of the whole adzuki bean genome using second-generation sequencing technology，Obtained90.88 GbValid sequence, assembledScaffold N50for1.29 Mbof466.7MbGenome sequence, accounting for adzuki bean genome (542 Mb)86.11%. useF₂Simplified sequencing of the population's genome to construct high resolutionSNPGenetic map and will372.9 MbThe sequence is riveted to the corresponding chromosome of Adzuki Bean,Assembled a high-quality adzuki bean genome framework. Genome annotation results display44.51%is a repeating sequence,Protein coding genes34,183pieces.Using comparative genomics to analyze the evolutionary relationship between adzuki beans and other legume species with known genomes，Comparison of genomes with known leguminous plants and collinearity analysis confirm that adzuki bean has the closest genetic relationship with common bean，There is good collinearity between the gene arrangement of multiple chromosomes of adzuki bean and the chromosomes of Phaseolus vulgaris。In view of the starch in adzuki bean and soybean grains(57.06%Bi25.3%)And grease（0.59%Bi22.5%）Accumulate differences, systemAnalysis of the composition and copy number of starch and oil anabolic pathway genes in adzuki bean and soybean genomes，And the transcription intensity of these genes during grain development，It is analyzed that the difference in starch and fat accumulation in adzuki bean and soybean grains is not caused by changes in the number of genes related to starch and oil synthesis，It is caused by the transcriptional expression of these genes。Yes49A serving of wild adzuki beans、Semi-wild adzuki beans、Resequencing analysis of farm varieties and modern cultivated varieties found a strong bet365 online sports betting appselection signal in the process of domestication of adzuki bean from wild species to cultivated species，And it is confirmed at the genome level that the relationship between semi-wild adzuki beans and cultivated adzuki beans is close to that of wild adzuki beans，It is speculated that semi-wild adzuki beans were the initial farm species in the process of domestication of adzuki beans。

Completion of whole genome sequencing of adzuki bean,It will greatly promote the research process on the molecular mechanisms of evolution and metabolic differences in legumes，Provides rich data resources for comparative genomics research，Provide support for the mining and molecular breeding of important agronomic trait genes of beans。